The calculation and manipulation of large multi-variable rational functions is a key bottleneck in multi-loop calculations. In these conference proceedings, based on my article [Chawdhry (2023) arXiv:2312.03672], I present a technique to interpolate such rational functions in a compact form by evaluating them at special integer points chosen for their properties under a p-adic absolute value. I apply the technique to examples of large rational functions appearing in 2-loop 5-point massless non-planar amplitude calculations in Quantum Chromodynamics (QCD). The number of required numerical probes (per field) is found to be around 25 times smaller than in conventional techniques, and the obtained result is 130 times smaller.