Recent results and state-of-the-art on top-quark pair production cross sections in both inclusive and differential measurements are presented, obtained using data collected with the CMS experiment during the LHC Run2 period at centre-of-mass energies ranging of 5.02 and 13TeV. Results are confronted against SM NLO and NNLO order predictions, several MC generators and tunes, and parton density function variations, with a special focus on the latest Run2 results.