In this talk, we discuss the calculation of the renormalization constant of the flavor-singlet axial-vector current with a non-anticommuting $\gamma_5$ in dimensional regularization determined to order $\alpha_s^3$ in QCD with massless quarks.
In addition we briefly comment on the subtlety in the renormalized form of an axial-current component of a given quark flavor, and the closely related renormalization formulae of the singlet contribution to an axial quark form factor, as well as the renormalization group equations.