The study of the associated production of vector bosons and jets constitutes an excellent testbench to check numerous QCD predictions. The most recent measurements of total and differential cross sections of vector bosons produced in association with jets are presented. Differential distributions as function of a broad range of kinematical observables are measured and compared with theoretical predictions. Final states with a vector boson and jets can be also used to study electroweak-initiated processes, such as the vector boson fusion production of a Z or W boson accompanied by a pair of energetic jets with large invariant mass. The study of these processes enables quantitative assessment of the reliability of the generator predictions for vector boson fusion topologies as well as stringent constraints on anomalous triple gauge coupling effective field theory parameters.