The Cherenkov Telescope Array (CTA) is an international initiative to build the next generation ground-based very-high-energy gamma-ray observatory. Full sky coverage will be assured by two arrays, one located on each of the northern and southern hemispheres. Three different sizes of telescopes will cover a wide energy range from tens of GeV up to hundreds of TeV. These telescopes, of which prototypes are currently under construction or completion, will have different mirror sizes and fields-of-view designed to access different energy regimes. Additionally, there will be groups of telescopes with different optics system, camera and electronics design. Given this diversity of instruments, an overall coherent calibration of the full array is a challenging task. Moreover, the CTA’s requirements on calibration accuracy are much more stringent than those achieved with current Imaging Atmospheric Cherenkov Telescopes, like for instance: the systematic errors in the energy scale must not exceed 10%. In this contribution we present both the methods that, applied directly to the acquired observational CTA data, will ensure that the calibration is correctly performed to the stringent required precision, and the calibration equipment that, external to the telescopes, is currently under development and testing. Moreover, some notes about the operative procedure to be followed with both methods and instruments, will be described. The methods applied to the observational CTA data include the analysis of muon ring images, of carefully selected cosmic-ray air shower images, of the reconstructed electron spectrum and that of known gamma-ray sources and the possible use of stereo techniques hardware-independent. These methods will be complemented with the use of calibrated light sources located on ground or on board unmanned aerial vehicles.