The All-Sky Medium Energy Gamma-ray Observatory (AMEGO) will survey the entire sky every three hours with its wide field of view and excellent continuum sensitivity between 200 keV and 10 GeV. This is a prime mission to study the long-term and short-term behavior of Active Galactic Nuclei (AGN) in the MeV range. Studying AGN that have their peak power output in the MeV band will allow us to determine the emission mechanisms underlying these extreme phenomenon. Furthermore, recent results from the Fermi Large Area Telescope have shown that MeV blazars are some of the most luminous and most distant gamma-ray AGN. A mission like AMEGO will provide the first ever census of AGN in the relatively unexplored MeV domain.